Optimasi Formulasi Masker Gel Peel-off dengan Ekstrak Kulit Putih  Buah Semangka (Citrullus lanatus) menggunakan Variasi Konsentrasi Karbopol 940: Optimization of the Peel-off  Gel Mask Formulation with Watermelon (Citrullus lanatus) White Peel Extract Using Variations in Carbopol  940 Concentrations

Widyani Budiarti; Hermini Tetrasari; Neni Rahmani; Dita Andhyni

doi:10.35706/pc.v6i1.13160

Authors

Widyani Budiarti Diploma-3 Farmasi Politeknik Bhakti Kartini, Bekasi, 17116, Indonesia
Hermini Tetrasari Diploma-3 Farmasi Politeknik Kesehatan Genesis Medicare, Depok, 16453, Indonesia
Neni Rahmani Diploma-3 Farmasi Politeknik Bhakti Kartini, Bekasi, 17116, Indonesia
Dita Andhyni Diploma-3 Farmasi Politeknik Kesehatan Genesis Medicare, Depok, 16453, Indonesia

DOI:

https://doi.org/10.35706/pc.v6i1.13160

Keywords:

Carbopol 940, Extract, Watermelon white rind, Face mask

Abstract

Antioxidant compounds were known to reduce the reactivity of free radicals, thereby helping to prevent damage to cells and bodily molecules. These compounds were commonly found in various plants and fruits and were considered relatively safer than synthetic antioxidants. In this study, the author utilized white rind extract of watermelon (Citrullus lanatus) as a natural antioxidant source in the formulation of a peel-off gel face mask intended for dry skin, using different concentrations of carbopol 940 as a gelling agent. An experimental method was employed, involving formulation development and product evaluation. Based on the assessment of three peel-off mask formulations containing 3.5% watermelon white rind extract, the optimal concentration of carbopol 940 was determined to be 0.5%. This conclusion was drawn from evaluations of homogeneity, organoleptic properties, spreadability, pH, viscosity, drying time, and product stability. The peel-off gel face mask formulated with 0.5% carbopol 940 and watermelon rind extract appears safe based on pH range and physical tests; however, further safety assessments.

Keywords: Carbopol 940; Extract; Watermelon white rind; Face mask.

Downloads

Download data is not yet available.

References

Adhisa, S., & Megasari, D. S. (2020). Kajian Penerapan Model Pembelajaran Kooperatif Tipe True or False pada Kompetensi Dasar Kelainan dan Penyakit Kulit. E-Jurnal Edisi Yudisium 3, 9(3), 82–90.

Alatas, A., & Anindhita, M. A. (2023). Pengaruh karbopol 940 sebagai gelling agent terhadap karakteristik fisikokimia sediaan masker gel peel-off ekstrak kulit buah melon oranye (Cucumis melo L.). BENZENA Pharmaceutical Scientific Journal, 1 (02).

Anggraeni, S. N. (2023). Optimasi Konsentrasi CMC-Na dan Propilenglikol Terhadap Sifat Fisik Masker Gel Peel-off Ekstrak Kulit Putih Semangka Merah (Citrullus lanatus) . Doctoral dissertation. Universitas dr. SOEBANDI).

Annisa, A., Kawareng, A. T., & Indriyanti, N. (2021). Formulasi Sediaan Masker Gel Peel Off dari Minyak Atsiri Sereh (Cymbopogon citratus): Formulation of the Preparation of Peel Off Gel Mask from Cymbopogon Citratus Essential Oil (Cymbopogon citratus). Proceeding of Mulawarman Pharmaceuticals Conferences, 14, 348–353. https://doi.org/10.25026/mpc.v14i1.599

Cantika, A. A. N., Putri, S. H., & Nurliasari, D. (2023). Pemanfaatan Limbah Kulit Buah Semangka (Citrullus Lanatus) Sebagai Antioksidan Alami Dalam Sediaan Masker Wajah Berbentuk Gel. . Jurnal Dialektika: Jurnal Ilmu Sosial, 21(2), 122–130.

Hamsinah, H. , V., Purnamasari, M., Amelia, M., & Aminah, A. (2023). Formulasi Masker Gel Peel Off Ekstrak Daun Tanaman Porang (Amorphophallus muelleri Blume) yang Stabil Secara Farmaseutik. Journal of Pharmaceutical and Health Research, 4(2),190–198. https://doi.org/10.47065/jharma.v4i2.3452

Irianti, T. T., & Pramono, S. (2022). Penuaan Dan Pencegahannya: Proses Faali Biokimiawi dan Molekuler (Siti, Ed.). Gajah Mada University Press Yogyakarta. https://doi.org/https://doi.org/10.21082/jpasca.v12n1.2015.11-19

Lestari, T. P., Putri, A. R., Kristianingsih, I., & Sari, F. (2022). Uji Stabilitas dan Uji Hedonik Masker Gel Peel-off Ekstrak Daun Binahong (Anredera cordifolia (Ten.) Steenis) Dengan Varian Konsentrasi Polivinil Alkohol (PVA) Sebagai Filming Agent. Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan, 8(2), 291–301. https://doi.org/10.51352/jim.v8i2.639

Nessa, N., Putri, N. R., Fitrianda, E., Elmitra, E., & Asra, R. (2020). Effect of Gel Formulation of Corn Silk Extract (Stigma Maydis) On Burn Wound Healing In Male White Rat. Asian Journal of Pharmaceutical Research and Development, 8(6), 20–27. https://doi.org/DOI:https://doi.org/10.22270/ajprd.v8i6.821

Numberi, A. M., Dewipratiwi, R., & Gunawan, E. (2020). Uji Stabilitas Fisik Sediaan Masker Gel dari Ekstrak Alga Merah (Poryphyra sp). Majalah Farmasetika, 5(1), 1–17.

Sibua, P., Simbala, E. I. H., & Datu, O. S. (2022). Uji Aktivitas Antioksidan Ekstrak Daun Pinang Yaki (Areca Vestiaria). PHARMACON Universitas Sam Ratulangi, 11(1), 1408–1416.

Siburian, S. (2020). Pencemaran Udaran dan Emisi Gas Rumah Kaca (Tim Kreasi Cendekia Pustaka, Ed.; 1st ed.). Kreasi Cendekia Pustaka.

Susianti, N., Juliantoni, Y., & Hanifa, N. I. (2021). Optimasi Sediaan Gel Ekstrak Buah Belimbing Wuluh (Averrhoa bilimbi L.) Dengan Variasi Basis Karbopol 940 Dan CMCNa. Acta Pharm Indo ,9(1),44–57. https://doi.org/https://doi.org/ 10.20884/1.api.2021.9.1.3669

Syachriyani, S., Arif, M., Agustikawati, D., P., F. F., & Farid, A. M. (2023). Potensi Imunomodulator Kombinasi Ekstrak Kulit Buah Semangka Merah (Citrullus lanatus) Dan Ekstrak Kulit Buah Naga Merah (Hylocereus polyrhizus) Terhadap Peningkatan Makrofag Mencit. Pharmacology and Pharmacy Scientifics Journals , 2(2),101–110.

https://doi.org/https://doi.org/10.51577/papsjournals.v2i2.468

Syam, N. R., Lestari, U., & Muhaimin, M. (2021). Formulasi dan Uji Sifat Fisik Masker Gel Peel Off Dari Minyak Sawit Murni Dengan Basis Carbomer 940 . Indonesian Journal of Pharma Science, 3(1), 42–55.

Thomas, N. A., Tungadi, R., Hiola, F., & Latif, M. S. (2023). Pengaruh Konsentrasi Karbopol 940 Sebagai Gelling Agent Terhadap Stabilitas Fisik Sediaan Gel Lidah Buaya (Aloe Vera). Indonesian Journal of Pharmaceutical Education, 3(2). https://doi.org/10.37311/ijpe.v3i2.18050

Wahyuni, D. F., Mustary, M., Syafruddin, S., & Deviyanti, D. (2022). Formulasi Masker Gel Peel Off dari Kulit Pisang Ambon (Musa Paradisiaca Var). Jurnal Sains Dan Kesehatan, 4(1), 48–55. https://doi.org/10.25026/jsk.v4i1.875

Wahyuni, F. E. , & Rochmah, N. N. (2022). Uji Aktivitas Antibakteri Sediaan Krim Kombinasi Ekstrak Kulit Batang Mangrove (Avicennia marina) dan Minyak A. Jurnal Ilmiah JOPHUS: Journal Of Pharmacy UMUS, 3(2), 75–84.

Wijaya, S. M., & Wening, S. (2021). Aktivitas Antioksidan dan Mutu Fisik Masker Wajah Berbahan Daun Kelor (Moringa Oleifera) dan Kopi Robusta (Coffea Canephora Var Robusta). Agrointek, 15(2), 537–543. https://doi.org/https://doi.org/10.21107/agrointek.v15i2.9592

Yusharyahya, S. N. (2021). Mekanisme Penuaan Kulit sebagai Dasar Pencegahan dan Pengobatan Kulit Menua. E-Journal Kesehatan Indonesia, 9(2), 150–159.