Efektivitas Senyawa Antioksidan dalam Saffron (Crocus Sativus L)

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Published: Sep 20, 2021
DOI: https://doi.org/10.35706/pc.v2i1.5579

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Wildani Zakiyah
Universitas Singaperbangsa Karawang
Anisa Fauziah
Universitas Singaperbangsa Karawang
Siti Farikha
Universitas Singaperbangsa Karawang
Nurlaela Nurlaela
Universitas Singaperbangsa Karawang
Irene Virda Sakina
Universitas Singaperbangsa Karawang
Lely Sulfiani Saula
Universitas Singaperbangsa Karawang

Abstract




Crocus sativus L atau dikenal di masyarakat sebagai saffron atau kuma-kuma yang berasal dari marga crocus dengan famili iridaceae. Kandungan utama di dalam saffron yaitu Crocin, Crocetin, Picrococin, dan safranal yang memiliki khasiat sebagai anti kanker, anti inflamasi, dan anti artritis. Kandungan antioksidan yang ada pada saffron diantaranya adalah senyawa fenolik dan karotenoid. Metode yang digunakan dalam pembuatan review artikel ini adalah pengumpulan literatur dari sumber jurnal yang ada yang berkaitan dengan safron (Crocus Sativus L), dimana pencarian literature jurnal yang bersumber dari Google, google scholar, libgen, dan pubmed. Pengujian antioksidan saffron menggunakan sel A549, crocin, dimethylcrocetin, crocetin, dan crocin. Selain iu ada pula apocarotenoid, cocetin, safranal. Eksrak saffron secara in vitro diuji dengan konsentrasi 200-2000 microgram/ml dapat menurunkan viabilitas sel MCF-7 dengan dosis waktu IC50 400 +/- 18,5 mikrog / ml setelah 48 jam.




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How to Cite
1.
Zakiyah W, Fauziah A, Farikha S, Nurlaela N, Sakina IV, Saula LS. Efektivitas Senyawa Antioksidan dalam Saffron (Crocus Sativus L). PharmaCine [Internet]. 2021Sep.20 [cited 2024Dec.27];2(1):36-42. Available from: https://journal.unsika.ac.id/pharmac/article/view/5579
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Vol. 2 No. 1 (2021): PharmaCine : Journal of Pharmacy, Medical and Health Science
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Artikel

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